Retinyl Propionate

Retinyl Propionate


  • CAS #: 7069-42-3 | EC #: 230-363-2
  • Chemical/IUPAC Name: Retinyl Propionate

Quick Facts

  • Also known as form of Retinoids and Retinol Ester
  • One of the lesser-known members of the retinoid family but still very potent
  • 3% of retinyl propionate in formulas help reduce the appearance of facial wrinkles and hyperpigmentation
  • Known for being the more gentle alternative for retinol without the worry of skin irritation
  • Can also deliver faster and more impressive results when introduced into your skincare routine

Who can use it?

Everyone, especially if they introduce it into their routine slowly and correctly to ensure there are no negative side effects.

What is Retinyl Propionate?

One of the lesser-known retinoids on the potent collection of retinol ester. Retinyl Propionate is a form of vitamin A that is effective at reducing the appearance of fine lines, wrinkles and the visibility of pores. It can rejuvenate the skin and restore an even tone and radiance. The difference, its molecular size is very large compared to retinol meaning it cannot reach too far down into the skin and cause too much irritation. This does mean it is gentle, but takes a little longer to show real results on the skin compared to other forms of vitamin A.

Side effects of Retinyl Propionate

Must be used in the evening and not overused to create irritation to the skin as it is still a potent form of vitamin A.

Scientific evidence of Retinyl Propionate

  • Green, C., et al. "A clinicopathological study of the effects of topical retinyl propionate cream in skin photoageing." Clinical and experimental dermatology 23 (1998): 162-167.
  • Fu, J. J. J., et al. "A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0· 02% tretinoin product regimen." British Journal of Dermatology 162.3 (2010): 647-654.
  • Draelos, Zoe Diana. "The latest cosmeceutical approaches for anti‐aging." Journal of Cosmetic Dermatology 6.s1 (2007): 2-6.
  • Fulton Jr, James E. "Composition and method for rejuvenating skin using vitamin A propionate." U.S. Patent No. 5,043,356. 27 Aug. 1991.


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